skip to content
Bio-Oligo Pro 400 Nucleic Acid Gene Synthesizer

Bio-Oligo Pro 400 Nucleic Acid Synthesizer

The Oligonucleotide Synthesizer features an explosion-proof design and complies fully with GMP production standards. The compact architecture and minimal footprint render it exceptionally suitable for pilot-scale operations, while its robust capacity ensures reliable and consistent batch production at the hundred-gram scale.

Technical Features of Bio-Oligo Pro 400 Nucleic Acid Gene Synthesizer Machine

01.

Biocompatibility

Incorporates a stacked piping configuration with minimal dead volume, designed to withstand conventional organic solvents such as acetonitrile and toluene, as well as dichloroacetic acid (3–10%) and other reactive reagents.

02.

Precision Flow Accuracy​

Constructed from high-grade stainless steel, the system incorporates three pump heads with integrated online mixing capability, delivering exceptional flow precision. Each pump head is equipped with an automated self-cleaning function for sustained performance.

03.

​Multi user management

Advanced software architecture supports multi-user access with hierarchical permission settings, enabling secure management, traceability, and operational accountability.

04.

Flexible Method Programming

An intuitive interface allows full customization of synthesis parameters and method editing, combining simplicity of operation with a refined human–machine interaction experience.

05.

Comprehensive Automation

The complete synthesis cycle is software-controlled, with continuous monitoring and recording of pressure, conductivity, and UV detection values to ensure rigorous process oversight.

06.

Individually customized

Tailored Customization Options extend to software configurations, synthesis columns, and reagent bottle specifications, providing adaptability to diverse research and production requirements.

07.

Regulatory Compliance

Software is designed in accordance with international regulatory frameworks, including 21 CFR Part 11, ensuring adherence to industry standards and facilitating validation for clinical and industrial applications.

Bio-Oligo Pro 400 Nucleic Acid/Gene Synthesizer Machine Specification

Infusion pump

Plunger pump, stainless steel material

Synthesis scale

4mmol-48mmol

Flow rate range

0~400ml/min

Number of individual entrances

11 (standard)

Operating pressure

15bar (218psi)

Maximum operating pressure

1

UV detector

4-channel UV detector, Wavelength range 200-800nm, accuracy ±1nm

Protective gas pressures

Nitrogen/Argon, 0.1~0.25bar, inlet tube size 6mm

Conductivity Detectors

Detection range 1uS/cm~300mS/cm

Exterior Dimensions

1430x1050x1940mm (L x W x H)

Power supply pressure

220V±5%AC

Power (output)

2000W

Pipeline material

PTFE tube

Related Products

Bio-Oligo Laboratory Nucleic Acid Synthesis Instrument

Bio Oligo Pro Series Production Grade Nucleic Acids

Bio Oligo Pro Series Production Grade Nucleic Acids

Oligonucleotide Synthesis Column

Oligonucleotide Synthesis Column

Frequently Asked Questions

The Bio-Oligo Pro 400 oligonucleotide synthesizer is designed for production on a pilot to 100-gram scale. Its GMP-compliant, explosion-proof design guarantees dependable, safe, and consistent synthesis for industrial and pharmaceutical production settings.

Contact Intech Analytical Instruments

Office Address

Plot no, 680, Rd Number 15, Vasanth Nagar, Kukatpally, Hyderabad, Telangana 500085

Lab Address

Plot No: 13, Sy No: 62/1/A,
Kakateeya Nagar, Bahadurpally, Dundigal,
Gandimaisamma, Medchal - 500043

Contact

Social Media :

Leave Your Message