Supercritical Fluid Chromatography
The strength, pressure, and temperature of the mobile phase can all be precisely controlled with Supercritical Fluid Chromatography, allowing for fine-grained modifications to the system’s selectivity and separation capacity. This adaptability makes it possible to precisely adjust the chromatographic parameters for the best separation and intended analytical results. This technology is harnessed by Supercritical Fluid Chromatography equipment, which provides efficiency and versatility in the analysis and purification of complicated mixtures.
Supercritical Fluid Chromatography (SFC) for Chiral Separation
The pharmacological importance of isomers in chiral pharmaceuticals has been highlighted in recent years due to increased regulatory scrutiny brought on by events like the “reaction stop” case. This is because of their unique biological activities. The following are the main approaches to chiral resolution:
- Crystallization
- Cleavage of chemicals
- Resolution in biology
- Chromatographic methods
While high-performance liquid chromatography (HPLC), which uses chiral stationary phases with great stability, has long been the standard for chiral separation, gas chromatography is used for volatile chiral substances. In recent years, HPLC has gradually lost ground to Supercritical Fluid Chromatography (SFC) as the method of choice for contemporary chiral separations because of SFC’s environmental friendliness, high efficiency, increased sample throughput, and lower operating costs.
Supercritical Fluid Chromatography
Analytical Supercritical Fluid Chromatography
SFC-Dynamic Axial Compression Column
CO₂ Booster Station
Frequently Asked Questions
Contact Intech Analytical Instruments
Office Address
Plot no, 680, Rd Number 15, Vasanth Nagar, Kukatpally, Hyderabad, Telangana 500085
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Plot No: 13, Sy No: 62/1/A,
Kakateeya Nagar, Bahadurpally, Dundigal,
Gandimaisamma, Medchal - 500043